Murat Bilgel, Ph.D.

Murat Bilgel, Ph.D.

Associate Scientist at the Brain Aging and Behavior Section, Laboratory of Behavioral Neuroscience, National Institute on Aging. All views are my own.

Publications

Skeletal muscle mitochondrial function predicts cognitive impairment and is associated with biomarkers of Alzheimer's disease and neurodegeneration

Published in Alzheimer's and Dementia, 2023 Aug

Qu Tian, Murat Bilgel, Keenan A. Walker, Abhay R. Moghekar, Kenneth W. Fishbein, Richard G. Spencer, Susan M. Resnick, Luigi Ferrucci, "Skeletal muscle mitochondrial function predicts cognitive impairment and is associated with biomarkers of Alzheimer's disease and neurodegeneration." Alzheimer's and Dementia, 2023.

White matter microstructural metrics are sensitively associated with clinical staging in Alzheimer’s disease

Published in Alzheimer's and Dementia, 2023 May

Yisu Yang, Kurt Schilling, Niranjana Shashikumar, Varuna Jasodanand, Elizabeth E. Moore, Kimberly R. Pechman, Murat Bilgel, Lori L. Beason-Held, Yang An, Andrea Shafer, Shannon L. Risacher, Bennett A. Landman, Angela L. Jefferson, Andrew J. Saykin, Susan M. Resnick, Timothy J. Hohman, Derek B. Archer, "White matter microstructural metrics are sensitively associated with clinical staging in Alzheimer's disease." Alzheimer's and Dementia, 2023.

Multi-method investigation of factors influencing amyloid onset and impairment in three cohorts

Published in Brain, 2022 Jul

Tobey Betthauser, Murat Bilgel, Rebecca Koscik, Bruno Jedynak, Yang An, Kristina Kellett, Abhay Moghekar, Erin Jonaitis, Charles Stone, Corinne Engelman, Sanjay Asthana, Bradley Christian, Dean Wong, Marilyn Albert, Susan Resnick, Sterling Johnson, Alzheimer’s Disease Neuroimaging Initiative, "Multi-method investigation of factors influencing amyloid onset and impairment in three cohorts." Brain, 2022.

Disentangling Alzheimer’s disease neurodegeneration from typical brain ageing using machine learning

Published in Brain Communications, 2022 May

Gyujoon Hwang, Ahmed Abdulkadir, Guray Erus, Mohamad Habes, Raymond Pomponio, Haochang Shou, Jimit Doshi, Elizabeth Mamourian, Tanweer Rashid, Murat Bilgel, Yong Fan, Aristeidis Sotiras, Dhivya Srinivasan, John Morris, Marilyn Albert, Nick Bryan, Susan Resnick, Ilya Nasrallah, Christos Davatzikos, David Wolk, "Disentangling Alzheimer’s disease neurodegeneration from typical brain ageing using machine learning." Brain Communications, 2022.

The Brain Chart of Aging: Machine-learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans

Published in Alzheimer's and Dementia, 2021 Sep

Mohamad Habes, Raymond Pomponio, Haochang Shou, Jimit Doshi, Elizabeth Mamourian, Guray Erus, Ilya Nasrallah, Lenore Launer, Tanweer Rashid, Murat Bilgel, Yong Fan, Jon Toledo, Kristine Yaffe, Aristeidis Sotiras, Dhivya Srinivasan, Mark Espeland, Colin Masters, Paul Maruff, Jurgen Fripp, Henry Völzk, Sterling Johnson, John Morris, Marilyn Albert, Michael Miller, R Bryan, Hans Grabe, Susan Resnick, David Wolk, Christos Davatzikos, "The Brain Chart of Aging: Machine-learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scans." Alzheimer’s & and Dementia, 2021.

Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study

Published in PLOS Medicine, 2021 May

Vijay Varma, Youjin Wang, Yang An, Sudhir Varma, Murat Bilgel, Jimit Doshi, Cristina Legido-Quigley, João Delgado, Anup Oommen, Jackson Roberts, Dean Wong, Christos Davatzikos, Susan Resnick, Juan Troncoso, Olga Pletnikova, Richard O’Brien, Eelko Hak, Brenda Baak, Ruth Pfeiffer, Priyanka Baloni, Siamak Mohmoudiandehkordi, Kwangsik Nho, Rima Kaddurah-Daouk, David Bennett, Shahinaz Gadalla, Madhav Thambisetty, "Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study." PLOS Medicine, 2021.

Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease

Published in JAMA Neurology, 2020 Jun

Neha Raghavan, Logan Dumitrescu, Elizabeth Mormino, Emily Mahoney, Annie Lee, Yizhe Gao, Murat Bilgel, David Goldstein, Theresa Harrison, Corinne Engelman, Andrew Saykin, Christopher Whelan, Jimmy Liu, William Jagust, Marilyn Albert, Sterling Johnson, Hyun-Sik Yang, Keith Johnson, Paul Aisen, Susan Resnick, Reisa Sperling, Philip Jager, Julie Schneider, David Bennett, Matthew Schrag, Badri Vardarajan, Timothy Hohman, Richard Mayeux, "Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease." JAMA Neurology, 2020.

Prediction of rapid amyloid and phosphorylated‐Tau accumulation in cognitively healthy individuals

Published in Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020 Jan

Ivan Koychev, Nemanja Vaci, Murat Bilgel, Yang An, Graciela Muniz, Dean Wong, John Gallacher, Abhay Mogekhar, Marilyn Albert, Susan Resnick, "Prediction of rapid amyloid and phosphorylated‐Tau accumulation in cognitively healthy individuals." Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020.

Association of peripheral inflammatory markers with connectivity in large-scale functional brain networks of non-demented older adults

Published in Brain, Behavior, and Immunity, 2020 Jan

Keenan Walker, Alden Gross, Abhay Moghekar, Anja Soldan, Corinne Pettigrew, Xirui Hou, Hanzhang Lu, Alfonso Alfini, Murat Bilgel, Michael Miller, Marilyn Albert, Jeremy Walston, "Association of peripheral inflammatory markers with connectivity in large-scale functional brain networks of non-demented older adults." Brain, Behavior, and Immunity, 2020.

Associations between Performance on an Abbreviated CogState Battery, Other Measures of Cognitive Function, and Biomarkers in People at Risk for Alzheimer's Disease

Published in Journal of Alzheimer's Disease, 2016 Jan

Annie Racine, Lindsay Clark, Sara Berman, Rebecca Koscik, Kimberly Mueller, Derek Norton, Christopher Nicholas, Kaj Blennow, Henrik Zetterberg, Bruno Jedynak, Murat Bilgel, Cynthia Carlsson, Bradley Christian, Sanjay Asthana, Sterling Johnson, "Associations between Performance on an Abbreviated CogState Battery, Other Measures of Cognitive Function, and Biomarkers in People at Risk for Alzheimer’s Disease." Journal of Alzheimer's Disease, 2016.

Temporal trajectory and progression score estimation from voxelwise longitudinal imaging measures: Application to amyloid imaging

Published in Lecture Notes in Computer Science (9123), Information Processing in Medical Imaging, 2015 Jan

Murat Bilgel, Bruno Jedynak, Dean Wong, Susan Resnick, Jerry Prince, "Temporal trajectory and progression score estimation from voxelwise longitudinal imaging measures: Application to amyloid imaging." Lecture Notes in Computer Science (9123), Information Processing in Medical Imaging, 2015.

Total synthesis of a functional designer eukaryotic chromosome

Published in Science, 2014 Apr

Narayana Annaluru, Héloïse Muller, Leslie Mitchell, Sivaprakash Ramalingam, Giovanni Stracquadanio, Sarah Richardson, Jessica Dymond, Zheng Kuang, Lisa Scheifele, Eric Cooper, Yizhi Cai, Karen Zeller, Neta Agmon, Jeffrey Han, Michalis Hadjithomas, Jennifer Tullman, Katrina Caravelli, Kimberly Cirelli, Zheyuan Guo, Viktoriya London, Apurva Yeluru, Sindurathy Murugan, Karthikeyan Kandavelou, Nicolas Agier, Gilles Fischer, Kun Yang, J Martin, Murat Bilgel, Pavlo Bohutski, Kristin Boulier, Brian Capaldo, Joy Chang, Kristie Charoen, Woo Choi, Peter Deng, James DiCarlo, Judy Doong, Jessilyn Dunn, Jason Feinberg, Christopher Fernandez, Charlotte Floria, David Gladowski, Pasha Hadidi, Isabel Ishizuka, Javaneh Jabbari, Calvin Lau, Pablo Lee, Sean Li, Denise Lin, Matthias Linder, Jonathan Ling, Jaime Liu, Jonathan Liu, Mariya London, Henry Ma, Jessica Mao, Jessica McDade, Alexandra McMillan, Aaron Moore, Won Oh, Yu Ouyang, Ruchi Patel, Marina Paul, Laura Paulsen, Judy Qiu, Alex Rhee, Matthew Rubashkin, Ina Soh, Nathaniel Sotuyo, Venkatesh Srinivas, Allison Suarez, Andy Wong, Remus Wong, Wei Xie, Yijie Xu, Allen Yu, Romain Koszul, Joel Bader, Jef Boeke, Srinivasan Chandrasegaran, "Total synthesis of a functional designer eukaryotic chromosome." Science, 2014.

Deformation field correction for spatial normalization of PET images using a population-derived partial least squares model

Published in Lecture Notes in Computer Science (8679), Machine Learning in Medical Imaging (MLMI), 2014 Jan

Murat Bilgel, Aaron Carass, Susan Resnick, Dean Wong, Jerry Prince, "Deformation field correction for spatial normalization of PET images using a population-derived partial least squares model." Lecture Notes in Computer Science (8679), Machine Learning in Medical Imaging (MLMI), 2014.